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Self grooming tips for men Get rid of unnecessary body hair:Hair on your ears, back, underarms, or uni-brows does not appeal at all. If you have them, then try and get a hair removing gel or wax away gently. Nose hairs can be trimmed from time to time, so that it's not visible. Hair in the underarms can either be waxed, or removed by using a razor. Hair on the back can also be removed through proper waxing. Shave properly:Keep a beard if it suits you, but do trim it regularly. If you do not want a beard, but just a moustache, then that requires customary trims as well. Try and keep yourself clean shaven, if you can't easily manage the styles mentioned above. Avoid bad breath:Bad breath can really get you into trouble, especially during office presentations, client meetings, or even at a date with your girlfriend. Use mouth washes to avoid this problem, and floss after every meal. Mouth fresheners can also come handy, so maintain a regular stock at all times. Brush regularly:Maintain a brush and floss routine twice a day to avoid awkward situations. Cut and clean your nails:Long nails look great on girls, but they are a big turn off in guys. Men need to keep their nails small and trimmed always. Use nail clippers to cut them properly, and cleaners to keep them clean. Take care of your skin:Buy a good sun care and moisturising lotion, and use it always, after a face wash and shower. This shall give you a nice glowing skin. Exercise regularly:A good body can attract everybody's attention. Eat healthy food and exercise regularly to be active and healthy. Get rid of body odour:Instead of colognes, try using deodorants and talcum powders to get rid of body odour. For underarms, always keep a roll-on with you, and apply it regularly. If the issue persists, then consult a doctor for help. Wear well fitting clothes:Wearing unfit or loose clothes will make you look older than you are. Hence, wear clothes which fit you the best. Correct your posture:While standing, walking, and even sitting, keep a straight back. This shall give u a better posture. You will look more pleasing and charming. Grooming is not just a thing for women. It is all about looking after yourself. So, read on to know some self grooming tips for men These were a few tips which can help you look after yourself better, and also give you that much needed edge over others. So, try them out right away!
Inspiring fitness goals for womenBeing fit comes with the benefit of enhanced mood and lowered hormonal rages. Coupled with right proportion of sleep, hydration, and a job you love, you will be nearing towards a perfect body. Goal 1: WorkOut Your Body to A Song! Make a playlist of all the songs you love and choose to execute your regime through it. Goal 2: "Be Yourself" Challenge Holistically develop your body by acknowledging what you love to do. Choose a sport that you love and join a group. If you love animals, then walk your dog which will let you lose weight and enjoy the company of pets. If painting or photography interests you, then trekking along landscapes of beauty should be your weekend getaway. Goal 3: Become the Hourglass with 1-Month Workout Regime Evaluate your body type and create a month-long regime to gradually progress towards animpeccable body shape and continue it beyond the initial 1 month. Start with small steps and do not go in for crash diets. Choose healthier snacks. Add a bit ofsleep to your daily dose in case you tend to sleep less. Begin with 15minutes of workout containing exercises recommended by your trainer to suit your body. Goal 4: Be the Health-Smart Mom! Lose the extra pounds you brought on during pregnancy and set a role model for your children. Go to the park with your children and play games with them. Pick up sports that you all can share and do together! Goal 5: The Yoga Guru Pick up yoga and start from the first step. Did you know that the initiation of anyone into the system of Yoga occurs through stage of Yama? Yama refers to the ethical principles that will guide your life while you move towards taking control of your life. The five Yamasin yoga are non-violence, truthfulness, non-stealing, celibacy, and non-possessiveness. They form the ground for your body to start on a healthy path. Move yourself towards following these principles and pick up the following asanas (body-postures) to lose weight: setu band (the bridge pose), bhekasana, dhanurasana, shalabhasana, chakki chalan, nauka chalan, and sarvangasana. A healthy lifestyle is the framework for any fitness goal. Do not go for unrealistic or transient goals. Start by making preparatory changes in your lifestyle: Lower your junk food intake, sleep adequately, drink at least two liters of water daily and hydrate your body sufficiently. Goal 6: Going Back to Nature Plan a trekking trip to your dream destination and walk your fat away. Bring back home a healthier body and a more peaceful mind. Goal 7: Master Your Body Make a journal of all activities you do in a day. The intention is to become aware of your habits that might be hurting your body unknowingly. Trace habits like binging on a snack while watching TV, sitting in a bad posture while on the desk and reading a book at a dimly lit place may be few pointers. This is a long-term challenge (4 months) to bring your body under your control through self-awareness. Goal 8: Green Regime Go for a diet which involves vegetables, fruits, and grains. Detoxify your body by being off junk food for at least two months. Goal 9: Bony to Healthy Increase your weight to become the inspiration for underweight people and guide them towards a healthy body. Goal 10: Run for the World Join marathons and runs for different social causes. Commonly known as 'Run for a Cause,' be the torchbearer to a certain cause by joining organizations that work on the same and initiating a run or marathon. This will not only prepare your body and move it towards healthy living; you will also be doing your part for the others.
Hairy tale: Hirsutism in womenThe condition is called Hirsutism where women grow coarse hair just like males on the face, chest or elsewhere. The primary cause for Hirsutism is hormonal imbalances by the over stimulation or excess production of male hormones (present in minute quantities in females too). The thickness of hair that grows largely depends on our genes and at times Hirsutism in women may be just a hereditary trait rather than an imbalance. Self care and medication can take of it in such a case. Idiopathic Hirsutism is a type of this condition where there is no possible cause for the male type hair growth. These women have regular menstrual cycles and no Androgen excesses, yet they have Hisrutism. Hirsutism with excessive bodily and facial hair, usually in a male pattern, in women may be present in normal adults as an expression of an ethnic characteristic or may develop in children or adults as the result of androgen excess due to tumors, or of non-androgenetic or other drugs. Hirsutism can make its appearance at menopause or soon after as there are a lot of hormonal changes that occur in the female body, and in certain cases women grow hair even on the lip, nipples, abdomen and upper shoulders. And just as men go bald there can also be a receding hairline and baldness in women accompanied by a deepening of the voice and enlargement of the clitoris. If the hair growth occurs at puberty then a doctor's evaluation is most essential as it could be more than just Hirsutism.
Your child is ready for school... but are you?It was still okay. Just 2-3 hours which you could utilize for other things while your child was away briefly. Now you will have to compete along with teachers, textbooks and homework for your child's attention. Well Mother, we know this is going to be difficult for you, but let's see if we can try and make it any easier. Think of school as an extension of the tender loving care that you provided. The only difference is that the TLC will go towards nurturing and developing his/her brain and help it learn important skills which will help gain a balanced development. At this point your child feels bad and completely unsafe in this new hostile world of teachers and uniforms and what not! If you weaken at this point your child will cop on and then will come the emotional blackmail. So explain the importance of school to your child as it will make the transition easier. It is always good for mothers to accompany their children to school but imagine watching mother walk away and all hell can break loose. So if your child's school has a school bus facility you can walk him to the bus stop and then say your goodbyes there. A lump in the throat at the bus stop is preferable any day than a scene at school with a child holding on to mother for dear life. Do not criticize your child's school or assignments given by them as children can catch on quite quickly and that can be reason enough for them not to concentrate on school activities. Always encourage your child to talk about what he did at school and ask him questions about his friends and teachers. This gives the impression that school is as important as home and gradually even you will reconcile yourself to the fact that school is here to stay.
Teenage troubles for autistic kidsTeenage brings along with it a lot of physical and psychological problems. Your body undergoes a lot of changes, the way the world looks at you is changing and you are not in the position to accept all this. Teenage is one of the most painful periods in one's life.  For an autistic child teenage can be compared to living a nightmare day in and day out. Here is a look at the problems of teenage from an autistic kid's point of view: Social Interaction The ability to interact socially is absent in autistic kids. They are loners who prefer to be left alone and undisturbed in their own worlds. Such a child is a natural target for bullying and ragging by other kids of his age group. At times even if the autistic child wants to come out and make friends, he is not able to do so due to lack of the required skills. Teenage is a period where you need at least one friend to confide in. It can be an extremely difficult phase when you are all alone. Puberty This is the dramatic time in life dilled with hormones and emotions. Your body undergoes lots of changes and you are confused about so many things. You don't know whom to ask or whom to turn to for guidance. Autistic children do not have the maturity to understand this phase. Special issues for autistic teens and sexuality include: Knowledge of physical changes in body. Knowledge of 'good' and 'bad' touch. Ability to communicate about a 'bad' touch or action. Keeping 'safe' distance from others. Handling menstrual cycles. Avoiding 'self-touch' in public. It can be a phase of emotional turmoil for the parents. They need to work closely with their child's special teachers to chalk out a plan that will be best suited to the child in handling puberty successfully. Self-help skills Simple self-help skills like hygiene can be a challenge for teenagers with autism. Improper motor skills, compliance, and sensory problems may interfere with a teen's progress. The proper training of hygiene and grooming can help to add these elements into the daily routine. The right approach is to simplify each task into simple small steps. The positive reward system is a great source of encouragement, as positive motivation always help the teenagers. Higher Functions Autistic teenagers are socially awkward. They lack the power to comprehend and process complex social cues which includes sarcasm, body language, humor, emotional responses and facial expressions. What complicates the problem is that the autistic child lacks empathy and hence may appear rude. Such kids are likely to be teased a lot in school settings.
Accepting your flawsThere are basically two kinds of 'flaws,' one that is physical and the other that is in your personality. A physical 'flaw' like being too short, fat, or darkis never a person's fault. Thus accepting what you are can only boost your self-esteem and confidence. Despite these 'shortcomings,' it is your character and your achievements that stand out in the long run and not the way you look. The first step in creating a better life is accepting if you are wrong! Personality traits and habits are mostly visible to others but not to you. These are those faults that can cause bitterness in relationships or cause problems at work or in our social interactions. Some people lose their temper easily, some are lazy, and some are rude, while some are either introverts or extroverts. If you have flaws that can cause problems for others then the best thing you can do is to change those negative traits in yourself. Character flaws might be natural, but they can affect others negatively. The first thing in making improvements is to analyze yourself. What are you so angry about ? Is it really some other person's fault or that you have had a bad day at the office? Give it a thought and once you find the answers, you will feel relieved. Accept your physical flaws and love yourself for what you are, as this is the key to lasting happiness. Major flaws like alcoholism, splurging money, borrowing money, or addictions are what one should be willing to overcome. If you accept you have any of these major flaws and need help to overcome them, then you need to seek help. There are professionals who can help out, provided you are a willing party to the process. Improvement will come only if you are willing to change. Remember that flaws are easy to acknowledge and to change;the only thing required is the desire within you to do so.
5 cardinal sins for the skinWhile cigarettes may not constitute food in the strictest sense, it does have a profound effect on skin complexion, health, color and tone. We eat that we may live, but sometimes we eat way too much and consume stuff that may be extremely hazardous to our health. Since we are talking about skin, here are 5 most hazardous foods for your skin: Grease adds to the crease Since healthy skin is all about healthy blood circulation, any food which is likely to clog up the blood vessels internally is deemed bad for skin tone. Packaged snacks like potato chips may have edible oil written in bold but this contributes significantly to the slowing down of 'collagen and elastin syntheses' which in turn causes the skin to appear aged and all wrinkly. The french fries that we consume as a TV snack can also cause an acne outbreak on the skin and face. Gluten Glutton Gluten is a substance found in wheat and other food grains. We may not even be aware that some of the food grains have gluten as a main constituent. Gluten intolerance can also cause inflammations on the skin in the form of rashes or acne. Bad news is that the pizzas, pastas, cakes and bread that we get off the rack may be heavy in gluten (Surprised that they don't say that on the pack) and that may be the reason for you to lose precious skin tone. So seek gluten free foods, though that might not be the easiest of tasks, but for your skin, it certainly will be worth it. Caffeine - the skin coffin If you are one of those coffee addicts then you may as well write an obituary column lamenting the loss of your skin tone and complexion. It's not without reason that health freaks love bashing coffee beans and caffeine rich beverages, as they are truly hazardous. How? Studies have proven that just 2-3 cups stimulate pituitary-adrenocortical response. Yes, but what does that have to do with your skin? Well this leads to the hormone cortisol to increase in our bodies. Cortisol is known as the stress hormone! So now here's what it does to your skin -it accelerates the ageing process which means wrinkled skin and causes dehydration causing the skin to show an unusual pallor. So before you turn the coffee faucet on think twice. Fad to Black How fad diets are not skin friendly? Some people go on a high protein, low-carb diet which could sound the death knell as far as complexion goes. Dieting depletes calcium levels, which means your bones are going to suffer and what's the point of having skin on bad bone density? Besides low-carb diets can utterly wreck the complexion as the delicate PH balance in the skin is ruined. Some of the meat, poultry and dairy products too can have artificial chemicals injected in them which cause a hormonal imbalance in our bodies leading to skin disasters. Fruits and vegetables have chemicals injected too sometimes! Beware! Cereal Killers Cereal killers are those people who ignore the need of a proper diet for skin health. So anybody who indulges in too much sugar, caffeine and greasy food stuffs is a 'Cereal Killer' A lack of cereals in the diet can literally kill your skin. Cereal foods have high fiber and antioxidants for moisturizing the skin and protecting it from skin damage. For great skin other than cereals which are simply fabulous for keeping skin hydrated and breathing easily, one can eat fruits, olive oil, healthy fats, almonds, tofu, grains, nuts and the good old vitamin B rich products. Ceramides in raw food diets, organic foods, wheat germ and brown rice protect the epidermis of the skin and make it impervious to external attacks and pollutants while maintaining their tone and beauty.
Aerobics: dancing your way to healthAerobic exercise is any comprehensive activity that makes you breathe hard while exercising your large muscle groups at a standard, even pace. The body uses stored carbohydrates and fats for energy. What is aerobics? Aerobic literally means having or providing oxygen or an activity that takes place only in the presence of oxygen. What is aerobic exercise? Aerobic exercise is any comprehensive activity that makes you breathe hard while exercising your large muscle groups at a standard, even pace. The body burns stored carbohydrates and fats for energy. Thus aerobic exercises help the body to utilize oxygen efficiently with increase in respiration and heart rate. What are the best ways to do aerobic exercises? There are number of ways by which you can exercise aerobically. Some easy and best ways are: walking, running, biking, using stationary bike, using stair stepper, elliptical machines or rowing machines, or joining an aerobic exercise class Benefits of aerobic exercises Fat reduction: Aerobics burns calories and body fats directly while using oxygen to produce energy. So this is the healthiest way to get rid of extra fat.  Strong heart: Aerobic exercises not only use your larger muscle groups like hamstrings, but also strengthen the heart muscles. This improves heart function resulting in improvement of blood and oxygen supply to all body parts, which provides healthy nourishment to body cell and removes toxins. Improves breathing: Exercises improve your lung capacity and function,which improves oxygenation, or competence of respiratory system to deliver oxygen to all body parts. It also improves overall health of the respiratory system. Cholesterol control: LDL cholesterol is bad cholesterol mostly responsible for clogging of arteries and HDL is good cholesterol. Aerobic exercises invariable increase the amount of HDL and lower LDL cholesterol thus preventing fat deposition and plaque formation and maintaining optimal blood supply to heart. Other benefits: Aerobics is the best exercise when it comes to prevention of various diseases like hypertension, diabetes, stroke and arthritis and osteoporosis. It helps to keep mood elevated and cures depression and boosts immunity. Make sure to incorporate some form of aerobic exercise in your daily routine.  
Thyroid may make your heart flutter!Thyroid is a small gland situated in the area of neck. In Greek, thyroid means the shape of a shield. Yes, thyroid gland is vital to a variety of important body functions and does act as a shield. But what happens when the shield is disturbed and goes weak? Thyroid dysfunction is recorded in approximately one to four people out of hundred Thyroid link to heart A research study was conducted in 2009 by Weill Cornell Medical College researchers. It was done to investigate and analyze the genetic link behind rhythm control of heartbeat. They found that the genes that are responsible for synchrony and rhythm in the functioning of heart are also closely connected to the thyroid hormone synthesis and could cause dysfunction of the thyroid. Thyroid activity directly influences the metabolism, blood flow and electrical activity of the heart. When there isn't enough thyroid hormone (low levels), the patients complain of low energy levels, fatigue and reduced heart rate. On the other hand, with increased thyroid hormone levels in the blood, patients report symptoms of hyperactivity of systems. There is diarrhea, palpitations, increased heartbeats and advanced cases show arrhythmias of heart, where normal beating rhythm of heart is disturbed and becomes irregular. Thyroid hyperactivity can be appropriately controlled with regular medication. Understanding arrhythmias When the rhythm of the heart is disturbed, it becomes irregular - this is called cardiac arrhythmia. There are various types of loss of rhythm - heartbeat is too slow (that is, the cycles are taking too long to complete), too fast (the cycles are repeating too quickly), too early (that is, before a cycle is even completed, another starts), too irregular (this is called fibrillation, where no specific pattern may emerge). The patients who have arrhythmia will often come with complaints of dizziness, shortness of breath, suddenly feeling weak or lightheaded, fainting and feeling of a flutter in chest (flutter can be understood as light but quick flapping of wings by a bird). Arrhythmias are usually harmless and most people would continue to live a healthy life for years with arrhythmias. But that does not mean it can be ignored. There is a battery of tests available to diagnose and indicate the seriousness of arrhythmias and let your doctor take a call on the line of treatment. If you have a thyroid dysfunction, get your heart checked immediately. And if you have faced arrhythmias, get your thyroid checked immediately. Both the conditions are controllable and treatable; there is no cause to worry over what could go wrong. Just be vigilant and informed.
Aids defining cancersIn fact the presence of such aids defining cancers is an indication of advanced AIDS having developed in these patients. However, the reasons for these cancers are unclear. It is possible that since people with AIDS have low immunity, they become more susceptible to these cancers. The double attack of these already complex diseases complicates treatment plans too. Thus, it needs care under experienced doctors who specialize in these diseases. The cancers that define AIDS are: Kaposi's Sarcoma:This is a type of skin cancer. It was usually found usually in people who have received organ transplants. Nowadays it is also most prevalent in homosexual men with HIV/AIDS and is also called epidemic Kaposi's Sarcoma.  It causes lesions to show up in multiple points in the body such as skin, lymph nodes, liver, lungs, spleen and digestive tract. Non-Hodgkin Lymphoma:This is the second most commonly associated cancer with HIV/AIDS. The various sub types of NHL are primary central nervous system lymphoma and primary effusion lymphoma. Approximately 4-10% people with HIV/AIDS develop NHL. Other kinds of cancers are anal cancer, liver cancer, mouth cancer, Hodgkin's lymphoma, testicular cancer, melanoma, throat cancer, colorectal cancer and multiple skin cancers.  Treating Cancer in HIV people: Till anti-HIV medication were not discovered the future for infected people was bleak. They were already sick and their bodies weak even before their cancer treatment were started. Presently the cancer treatment is mixed with anti-HIV drugs. However, depending upon the extent of cancer and the need of AIDS care, variations are made between chemotherapy and other HIV related drugs needed. Treating Kaposi's Sarcoma: Often anti-HIV drugs are enough to treat this cancer. The lesions, which are viral, shrink, as the immune system gets better. Sometimes chemotherapy and radiation may also be needed if the lesions are internal. Treating Non-Hodgkin Lymphoma: AIDS related NHL is fast growing and needs intense chemotherapy treatment. Introduction of highly active anti-retroviral therapy and use of drugs that help the infected body make new blood cells has relieved a major concern for HIV patients where previously due to their low blood cell count, chemotherapy could not be administered to them. But with these advances, acutely monitored chemotherapy treatments can be administered now. Treating Cervical Cancer: In case of women who have a good immune system and invasive cervical cancer can still be treated similarly as non-HIV women. They can even do well in surgeries and other conventional treatments. Discovering Cancer Early: Screening helps discover presence of cancer when no symptoms are evident. However AIDS defining cancers cannot be detected through screening. Thus, close monitoring, regular checkups and a keen lookout for symptoms of these cancers can help discover the ailment if present. Pap tests help discover cervical cancer in women. However, in case of HIV women, these should be undertaken more often. Even as often as 2 tests a year, 6 months apart in the first year of HIV detection. If the tests are clear, they should get Pap tests done regularly once a year henceforth. For other AIDS related cancers, the screening tests are still being devised. Lowering Cancer Risk: HIV ruins the body's immune system making it susceptible to a variety of diseases. Good health practices are a must for those detected with HIV in order to ward off cancer. They should surely not smoke or consume alcohol. Injection drugs and unsafe sexual practices also pose increased threat of cancer. Maintaining balanced diets, physical activity and proper body weight are extremely important and helpful too.
Pulling out - Is it an effective option for contraception?What is the 'Pulling out' method? 'Pulling out', 'Withdrawal' and 'Coitus Interruptus' are all the different names for probably one of the safest methods of contraception. It involves the male partner withdrawing or pulling out his penis just before ejaculation. This ensures that no semen has been ejaculated into the vagina or vulva of the female partner. Since there are no sperms travelling inside, the result is - No Pregnancy! Is this method really effective? Like all methods of contraception, the effectiveness of the pulling out method also depends on how correctly it is done. This method requires a lot of mutual understanding between the partners. The male partner must also exercise great self-control and accuracy in knowing when he will reach the highest point of sexual excitement so he can pull out at the right moment. Statistics have the following things to say Of women whose partners use withdrawal, 4% become pregnant each year if they always do it correctly, and 27% become pregnant each year if they don't always do it correctly. Ejaculating close to the vagina or vulva would mean that the sperms still have a way to travel inside the vagina. At times the pre-ejaculate fluid may also contain a few sperms from the previous ejaculation that may end up causing pregnancy. As a precaution against this, experts suggest the male partner pass urine before the sexual act. Withdrawal method of contraception is the best option for members of religious groups in which using contraceptive devices like pills, condoms or IUDs are a form of sin. Withdrawal method does not protect you from HIV/AIDS and other STDs. What are the advantages and disadvantages of this method? Advantages It is simple, safe and convenient. It is the best method when no other contraceptive method is available. It has no side-effects It does not require a medical prescription. It does not alter the menstrual cycle. It does not affect future fertility. Disadvantages Requires great self-control, experience and trust. Not suitable for men who suffer from premature ejaculation Not suitable for teenagers and sexually inexperienced people. Does not ensure protection from sexually transmitted diseases and HIV/AIDS. Less effective than other methods of birth control. May interfere with sexual pleasure due to nervousness and anticipation of pulling out at the right time. The pull out method is thus one of the safest methods of contraception, provided one has a thorough understanding of one's body, trust in the partner and a huge amount of self-control.
The link between oral sex and cancerSymptoms of oral cancer: The common symptoms of oral cancer include: Red and white spots on the tongue or the lining of the mouth, inflammation of the mouth which continues well over two weeks, mouth ulcers which take over three weeks to heal, discomfort and pain during swallowing food, and lastly, sensation that something is stuck in the throat. HPV types and their nature: There are over 100 different types of HPV. Out of these, 15 have been found to cause cancer. These 15 types of HPV are called high-risk HPV. The HPV types which are found in the mouth are sexually communicable and the primary means for its transference is considered to be oral sex. It could also be carried through anal and vaginal sex, causing laryngeal cancer, anal cancer, cervical cancer, tonsil cancer, vulval and vaginal cancer, and penile cancer. Some of the HPV types get passed through skin contact. These cause warts, especially in the genital region. These types of HPV which cause the warts are less likely to escalate and cause cancer. Though there is no determinate answer as to how common the HPV mouth infection is. Advanced studies during the 21st century have put forward the role of HPV16 in new types of cancer. This was done using DNA testing. Through a medical study, it was found that the most vulnerable groups are: People in the age group of 30 to 34 and 60 to 64 years old. People who have had over 20 sexual partners in their lifetime, around 20% suffer from HPV oral infection HPV leads to cancer?: HPV does not directly cause cancer. It stimulates modifications in the cells which it has infected, like those in the mouth or cervix and due to the modifications the cell becomes cancerous. In only 10% of the cases where the patient suffers from HPV infection does cancer develop. The infection generally treats itself and is removed naturally within 2 years by the body. The chances of progression of the HPV infection into cancer is increased by smoking and drinking. Smoking injures the immune surveillance cells. Due to this injury, they are not able to fight the virus and the virus continues to persist over 2 years, leading to cancer. Vaccinations: In the United Kingdom, girls (aged 12 and 13 years old) are vaccinated against HPV. This vaccination protects the women against cervical, vulval, and vaginal cancers. Men and boys also take vaccinations against HPV, though it is not pursued as strongly as in the case of women. This leaves men who have sex with other men at a greater risk of getting oral and anal cancer. Even though the link between oral sex and cancer is not completely proven, what we do know is that oral sex causes many other infections like gonorrhea, herpes, syphilis, and chlamydia. Did you know that a very low percentage of people (only 10%) who are infected with HPV virus develop cancer? In 90% of the cases, the infection is naturally cleared by the body within two years. The natural process is, however, obstructed in those who smoke and drink.    
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